| ORIGINAL ARTICLE |
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| Year : 2017 | Volume
: 14
| Issue : 3 | Page : 154-159 |
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Effect of risk factors on grades of gastroesophageal reflux disease
Batool Mutar Mahdi1, Riyadh Mohamad Hasan2, Wafaa Hazim3
1 Department of Microbiology, HLA Typing Research Unit, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
2 Department of Surgery, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
3 Department of Microbiology, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
Correspondence Address:
Batool Mutar Mahdi
Department of Microbiology, HLA Typing Research Unit, Al-Kindy College of Medicine, University of Baghdad, Al-Nahda Square, Baghdad
Iraq
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/am.am_38_17
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Background: There are many risk factors associated with degree of development erosive esophagitis and its complications. Aim of the Study: To evaluate the effect of risk factors on severity of esophagitis and identify the most important risk factors among patients presenting to gastroscopy unit. Patients and Methods: Patients with upper gastrointestinal tract (GIT) symptoms were enrolled in gastroscope examination. For each participant, the body mass index (BMI), waist circumference, and immunoglobulin G Helicobacter pylori were done. Results: A total of 195 patients with upper GIT symptoms were examined by gastroscope. One hundred and twenty patients had erosive esophagitis (Grade II and III) (Group A): 75 of them were men (62.5%) and 45 (37.5%) were women. The rest 75 had gastroesophageal reflux disease Grade I (Group B), 52% of them were males, and the rest were females. Group A patients were more likely to be non-steroidal anti-inflammatory (NSAID) users (42.5%) than Group B (P = 0.0002). Group A was more likely to be obese (body mass index >30) (37.5%) (P = 0.015). Men have waist circumference >102 cm and women have a waist circumference >88 cm constitute 92.5% (P = 0.0001) of Group A. Patient with Group A who had hiatus hernia (HH) were (20%) (P = 0.0001) and those with H. pylori (35%) (P = 0.001). Conclusions: Obesity, abdominal obesity, NSAID, HH, and H. pylori infection are strong risk factors for gastroesophageal reflux grades.
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