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Table of Contents
Year : 2022  |  Volume : 19  |  Issue : 2  |  Page : 126-127

Distinct differences were noticed during the 3rd COVID wave in India

Department of Orthopaedics, Indraprasth Apollo Hospitals, New Delhi, India

Date of Submission18-Feb-2022
Date of Decision04-Mar-2022
Date of Acceptance05-Mar-2022
Date of Web Publication06-May-2022

Correspondence Address:
Jay V Turakhiya
Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/am.am_30_22

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How to cite this article:
Turakhiya JV, Vaish A. Distinct differences were noticed during the 3rd COVID wave in India. Apollo Med 2022;19:126-7

How to cite this URL:
Turakhiya JV, Vaish A. Distinct differences were noticed during the 3rd COVID wave in India. Apollo Med [serial online] 2022 [cited 2022 Jul 1];19:126-7. Available from: https://www.apollomedicine.org/text.asp?2022/19/2/126/344872


India is now facing the third wave of COVID-19 since January 2022. The total reported cases on COVID-19 until now have been 40.3 million (second highest after the USA), with a death rate of 1.2% [Table 1].[1] More than 164 million COVID vaccinations have been done so far; with a single dose in 56.97%, two doses in 42.42%, and the 3rd or precaution dose in 0.6% of the population.[2]
Table 1: Statistics of COVID-19 in India

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  Differences in the Three Waves Top

Recent mutant Omicron virus has taken over all other strains and driving this wave. It has shown a high transmission rate and a shorter incubation. In the 2nd wave, the pediatric and younger individuals were getting infected, in addition to older ones.[3] We have distinguished between the three waves of COVID-19 [Table 2]. Jain et al. had earlier elucidated the differences between the first and second COVID waves.[4]
Table 2: Differences between the first, second, and third wave of COVID-19 in India

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This Variant of Concern can easily bypass or escape the immunity of the vaccinated people and those who have had prior infection. However, it primarily affects Upper Respiratory Tract and as a result, the infected people got away with a minor illness in most cases, and the mortality rates were low. Requirement for hospital and intensive care unit beds, oxygen therapy, and ventilators was also much less this time.[5] Since we knew much more about COVID-19, the world was better prepared to deal with it. Several unproven therapies such as the use of some antivirals, antibiotics, and plasma therapy were excluded from the recommendation of various organizations. Importantly, a large population was vaccinated this time [Table 1], which helped them get less severe disease. The occurrence of breakthrough infections confirms that the current COVID vaccines can fully prevent the reinfection but are surely act as a disease-modifying agent and reduce the severity of reinfection.

The risk factors related to the severity of the COVID-19 have now been understood. Unvaccinated and older people and those with comorbidities such as Diabetes Mellitus, lung diseases, immune-compromised status are likely to have much severe illness, complications, and deaths. Soetedjo et al. have found that the antibody response and seropositivity after the COVID-19 vaccine were lower in people with diabetes than healthy subjects. It may be the reason for more severe disease in diabetics and people with other risk factors.[6]

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Conflicts of interest

There are no conflicts of interest.

  References Top

WHO. Available from: https://covid19.who.int/table. [Last accessed on 2022 Jan 28].  Back to cited text no. 1
COWIN. Available from: https://dashboard.cowin.gov.in/. [Last accessed on 2022 Jan 28].  Back to cited text no. 2
Hippich M, Sifft P, Zapardiel-Gonzalo J, Böhmer MM, Lampasona V, et al. A public health antibody screening indicates a marked increase in SARS-CoV-2 exposure rate in children during the second wave. Med (N Y) 2021;2:571-2.  Back to cited text no. 3
Jain VK, Iyengar KP, Vaishya R. Differences between First wave and Second wave of COVID-19 in India. Diabetes Metab Syndr 2021;15:1047-8.  Back to cited text no. 4
Taboada M, González M, Alvarez A, Eiras M, Costa J, Álvarez J, et al. First, second and third wave of COVID-19. What have we changed in the ICU management of these patients? J Infect 2021;82:14-5.  Back to cited text no. 5
Soetedjo NN, Iryaningrum MR, Lawrensia S, Permana H. Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review. Diabetes Metab Syndr 2022;16:102406.  Back to cited text no. 6


  [Table 1], [Table 2]


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