Apollo Medicine

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 15  |  Issue : 2  |  Page : 94--98

Comparative burdens of atherosclerosis in rural and urban communities in South India: Insights from the Kovai Medical Center and Hospital-noncommunicable disease studies


Ganesh Veerasekar1, Krishnan Swaminathan1, Mohanraj Sundaresan2, Chitra Ramanathan2, Ganesan Velmurugan3, Thomas Alexander4, Nalla G Palaniswami1, Mathew Cherian4 
1 KMCH Research Foundation; Kovai Medical Center and Hospital Ltd., Coimbatore, Tamil Nadu, India
2 KMCH Research Foundation, Coimbatore, Tamil Nadu, India
3 Department of Chemistry, DST Unit of Nanoscience, IIT Madras, Chennai, Tamil Nadu, India
4 Kovai Medical Center and Hospital Ltd., Coimbatore, India

Correspondence Address:
Krishnan Swaminathan
KMCH Research Foundation, Kovai Medical Center and Hospital Ltd., Coimbatore - 641 014, Tamil Nadu
India

Aim: The aim of this study was to describe the distribution and comparison of carotid intima thickness in two completely different demographics in South India. Materials and Methods: Data were obtained from 865 participants in rural Nallampatti and 1081 participants from urban Kalapatti in the state of Tamil Nadu. Local ethics committee approval and written and informed consent were obtained from all participants. Carotid intima thickness was measured on all participants using high-resolution B-mode ultrasound. Atherosclerosis was defined as a carotid intima-media thickness of ≥1 mm. Results: The prevalence of atherosclerosis was 10.3% in rural Nallampatti compared to 7.8% in urban Kalapatti. On binary logistic regression analysis, diabetes and hypertension were associated with atherosclerosis in rural areas, but this significance disappeared after adjustment for confounding factors. In urban areas, diabetes appeared to be significantly associated with atherosclerosis even after adjustment for confounding factors. Conclusion: Our data suggest a surprisingly increased prevalence of atherosclerosis in a rural farming population even though traditional risk factors for atherosclerosis such as diabetes and hypertension did not show a significant association after adjustment for confounding factors. If confirmed, this provides a rationale to do large-scale studies to explore the role of nontraditional risk factors in rural India that could have an impact on atherosclerosis and cardiovascular disease.


How to cite this article:
Veerasekar G, Swaminathan K, Sundaresan M, Ramanathan C, Velmurugan G, Alexander T, Palaniswami NG, Cherian M. Comparative burdens of atherosclerosis in rural and urban communities in South India: Insights from the Kovai Medical Center and Hospital-noncommunicable disease studies.Apollo Med 2018;15:94-98


How to cite this URL:
Veerasekar G, Swaminathan K, Sundaresan M, Ramanathan C, Velmurugan G, Alexander T, Palaniswami NG, Cherian M. Comparative burdens of atherosclerosis in rural and urban communities in South India: Insights from the Kovai Medical Center and Hospital-noncommunicable disease studies. Apollo Med [serial online] 2018 [cited 2023 Jan 27 ];15:94-98
Available from: https://apollomedicine.org/article.asp?issn=0976-0016;year=2018;volume=15;issue=2;spage=94;epage=98;aulast=Veerasekar;type=0