Apollo Medicine

CASE REPORT
Year
: 2019  |  Volume : 16  |  Issue : 1  |  Page : 33--35

Aggressive surgical resection following neoadjuvant imatinib therapy for advanced duodenal tumor with hepatic metastasis


Varun Madaan, Rigved Gupta, GK Adithya, Satya Prakash Jindal, Deepak Govil 
 Department of Surgical Gastroenterology, Indraprastha Apollo Hospital, New Delhi, India

Correspondence Address:
Varun Madaan
Department of Surgical Gastroenterology, Indraprastha Apollo Hospital, Opd No. 1241, New Delhi
India

Duodenal gastrointestinal stromal tumors (GISTs) are rare tumors which constitute <5% of all cases of GIST. The treatment of locally advanced/inoperable and metastatic GIST is primarily tyrosine kinase inhibitor therapy (TKI), i.e., imatinib mesylate. In some patients, initial TKI therapy may result in significant downstaging of the primary tumor and metastatic disease. The role of aggressive surgical resection in such patients remains controversial. We present a case of advanced duodenal GIST treated successfully by Whipple's procedure with liver wedge resection following neoadjuvant TKI therapy. This case shows that aggressive surgical resection for metastatic duodenal GIST following neoadjuvant imatinib seems to be a feasible treatment option.


How to cite this article:
Madaan V, Gupta R, Adithya G K, Jindal SP, Govil D. Aggressive surgical resection following neoadjuvant imatinib therapy for advanced duodenal tumor with hepatic metastasis.Apollo Med 2019;16:33-35


How to cite this URL:
Madaan V, Gupta R, Adithya G K, Jindal SP, Govil D. Aggressive surgical resection following neoadjuvant imatinib therapy for advanced duodenal tumor with hepatic metastasis. Apollo Med [serial online] 2019 [cited 2023 Jan 27 ];16:33-35
Available from: https://apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=1;spage=33;epage=35;aulast=Madaan;type=0