Apollo Medicine

CASE REPORT
Year
: 2022  |  Volume : 19  |  Issue : 4  |  Page : 262--263

Spuriously low thyroid-stimulating hormone? A laboratory phenomenon


S Danalakshmi1, Mamta Soni2 
1 Department of Biochemistry, Apollo Hospitals, Chennai, Tamil Nadu, India
2 Department of Hematology and Clinical Pathology, Apollo Hospitals, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Mamta Soni
Department of Hematology and Clinical Pathology, Apollo Hospitals, 21 Greams Lane, Off. Greams Road, Chennai - 600 031, Tamil Nadu
India

Thyroid gland is an endocrine gland with vital functions regulating metabolism, growth, and development. The tests used to assess the functions of the thyroid gland include thyroid-stimulating hormone (TSH), free thyroxine, and free tri-iodothyronine. TSH is routinely measured in the clinical laboratory with automated immunoassays to diagnose and monitor thyroid disorders. We present a case wherein the discrepancy between the clinical symptoms and the biochemical test results raised the possibility of methodological interference in laboratory testing, finally leading to a detection of a rare genetic mutation in the patient. This case reiterates that clinical correlation of laboratory results and effective communication between the clinician and the laboratory are imperative for a correct diagnosis and therapeutic interventions.


How to cite this article:
Danalakshmi S, Soni M. Spuriously low thyroid-stimulating hormone? A laboratory phenomenon.Apollo Med 2022;19:262-263


How to cite this URL:
Danalakshmi S, Soni M. Spuriously low thyroid-stimulating hormone? A laboratory phenomenon. Apollo Med [serial online] 2022 [cited 2023 Mar 22 ];19:262-263
Available from: https://apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=4;spage=262;epage=263;aulast=Danalakshmi;type=0